In 1837, William Procter and James Gamble started making and selling soap and candles in Cincinnati, Ohio. This marked the beginning of a rich heritage of soap making for Procter & Gamble.For more than 50 years, Safeguard has delivered on the commitment to provide the best protection against disease-causing germs of any antibacterial soap. With a presence in more than 15 countries, Safeguard continues to introduce new innovations and education programs that help make families smarter and stronger in the fight against harmful germs.